After Hypertensive Disorders of Pregnancy, HTN Up 10 Years

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The researchers found that compared with those without HDP, patients with a history of HDP had an increased risk for new hypertension (56.0 versus 23.5 percent; adjusted relative risk, 2.4); measures of left ventricular structure, global longitudinal strain, diastolic function, arterial stiffness, or endothelial function did not differ. Regardless of HDP history, compared with those without hypertension, patients who developed hypertension had greater left ventricular remodeling, including greater relative wall thickness; worse diastolic function including lower septal and lateral e’ and E/A ratio; more abnormal longitudinal strain; and higher effective arterial elastance.

Story Highlights

  • Lisa D. Levine, M.D., from the University of Pennsylvania Perelman School of Medicine in Philadelphia, and colleagues conducted a prospective study of patients with and without a diagnosis of HDP about 10 years earlier (2005 to 2007). A total of 135 patients (84 with and 51 without a history of HDP) underwent assessments with echocardiography, arterial tonometry, and flow-mediated dilation of the brachial artery.